Ampoule Specialist · Since 2009

Formulated, filled and finished in one facility.

A dermo-cosmetics manufacturer trusted by partners in twelve markets. Our Skin Science R&D Center designs the formula, and our ISO 22716 smart factory records every vial.

Corporate Skin Science R&D CenterPatented Bio-Peptone® ingredientMES smart factoryPrompt replies, in order received
  • 20,000vials/dayAmpoule filling capacity8 dedicated ampoule lines
  • 18.2MΩ·cmUltrapure process waterMeasured after 5-stage filtration
  • 8Registered patents7 publications · ICID-listed ingredient
  • 12Export marketsSupplying since 2010

R&D Technology

Our Skin Science R&D Center designs the formula

A corporate-affiliated research institute, first recognized in 2009. Ingredient development, skin delivery, ampoule stability and efficacy testing sit with one team, so your product can carry a formula other manufacturers cannot copy.

A Janytree researcher checking ampoule formulation ingredients at the raw material shelves
SKIN SCIENCE R&D CENTER

Dermo-Cell Science Platform

From ingredient to evidence, in four steps

  1. 01 IngredientBio-Peptone® fermented bio-material
  2. 02 DeliveryNano-liposome · TDDS transdermal delivery
  3. 03 FormulaHigh-concentration ampoule stability · vial filling
  4. 04 EvidenceHuman application tests · export efficacy dossiers
ICID-listed ingredient8 patents7 publications3 government R&D programs
TECH 01 · PROPRIETARY

Bio-Peptone®

A fermented peptide developed in our own laboratory, protected by patent and listed in the International Cosmetic Ingredient Dictionary (Monograph ID 32729).

FOR PARTNERSA core active for your own regeneration and barrier ampoules

TECH 02 · FERMENTATION

Fermentation bio-conversion

48 hours of anaerobic fermentation raises enzyme activity while preventing toxin release. Smaller molecules absorb into the skin more easily.

FOR PARTNERSLow-irritation, high-performance lines for sensitive skin

TECH 03 · DELIVERY

Nano-liposome

A lipid bilayer that mimics the cell membrane carries both water- and oil-soluble actives. An average particle size of 250 nm reaches between skin cells.

FOR PARTNERSHigh-concentration ampoules and serums

TECH 04 · DEVICE SYNERGY

TDDS transdermal delivery

Formulas designed to work with beauty devices and microneedling, delivering actives into deeper skin layers. Produced to KGMP standards since 2009.

FOR PARTNERSSkin boosters for clinics and aesthetic treatments

Want an ampoule built on this science? A researcher will handle your first consultation.

Plan a product with us

OEM / ODM Solutions

20,000 ampoules a day, on dedicated lines

Eight production lines are specialized for ampoule formats, and serums, toners, creams and fragrance run on the same equipment discipline. Partners ordering a few SKUs in modest quantities get the same process control as a single large run.

Ampoule vial production line
420,000Ampoules (vials) per month · dedicated lines
Product linePer dayPer month
Ampoule (vial) · skin / scalp20,000420,000
Essence / Serum5,000105,000
Toner5,000105,000
Mist5,000105,000
Cleanser / Shampoo5,000105,000
Fragrance5,000105,000
Lotion3,00063,000
Cream3,00063,000

Bottles per unit of time. Monthly figures assume 21 production days.

How we work

From first inquiry to shipment in 7 steps

No formula yet? A concept is enough to start. Every step is logged against its batch in our MES, so you can see how your product was made.

  1. Inquiry

    Concept, target market and desired benefits

  2. Contract

    NDA, development scope and schedule

  3. Formula & sample

    Lab formulation and sample approval

  4. Materials in

    Receipt inspection and traceability

  5. Bulk

    Precision weighing and in-process checks

  6. Finished goods

    Filling, packing and final inspection

  7. Release

    Domestic delivery and export documents

Inquiries are processed in the order received, and we will get back to you as soon as possible.

B2B Inquiry

Quality & Smart Factory

Every batch has a record, and we can show it

Raw-material receipt, weighing, compounding, filling, packaging, in-process inspection and release are each logged as they happen. Traceability is not reconstructed afterwards from paper.

Ultra-pure purified water

PURIFIED WATER

70% of cosmetics is water

Five-stage filtration and endotoxin removal produce the ultra-pure, pyrogen-free water that every product starts from.

See our water system →
Keyence AI vision system screen inspecting ampoule vials for particles

AI + HUMAN

Vision inspection plus a human check

Two vision systems and a checkweigher reject underfilled or badly sealed units, and inspectors check every vial again before packing.

See the 6-step inspection →
Labelled and tagged raw materials tracked in the Janytree storage room

MES · SMART FACTORY

Batch-level MES traceability

Lab recipes carry straight into production scale. Government-accredited smart factory, Manufacturing Innovation Capability Level 2 (2024).

See our smart factory →
ISO 22716 (CGMP)KR005043 · Bureau Veritas
Smart factory Level 22024 · Government accredited
Promising Export SMEDesignated 2012
Venture · Women EnterpriseCertified 2011
KOTRA global expansion programSelected 2025

Portfolio

What we make under our own name

INTOMEDI is Janytree's own brand — four lines, twelve products, developed and manufactured in house. It is where our formulations are proven before they are offered to partner brands.

INTOMEDI CLINIX REJUE, WHITE and HYDRO ampoule boosters
In-house brand

INTOMEDI

A dermo-cosmetics brand created by skin researchers and skincare professionals, from clinic-only lines to home care, exported to Russia, Turkey, India, China and more.

See our brands
PROFESSIONAL · 5 PRODUCTS

CLINIX

Clinic and aesthetic channel. Firming, brightening and hydrating ampoules, plus a two-step peeling program.

SCALP & HAIR · 1 PRODUCT

HR PEPTIDE

Beyond skincare, built on our fermented peptone patents.

BARRIER & SOOTHING · 3 PRODUCTS

CALMER

For dry, oily and sensitive skin. The line carrying the most human application test data.

DAILY HYDRATION · 3 PRODUCTS

AMPLANCE HYDRO

Cleanse, boost and seal. The skin-barrier line, launched 2020.

Partner products are shared during consultation, with samples, within the limits of each contract.

Global Export

12markets

Going abroad? We start with the paperwork.

  • Twelve markets continuously supplied since 2010
  • Support for country-specific regulatory and technical documents
  • China hygiene licenses held for four products
  • Efficacy substantiation dossiers for export (PIF)
Talk to our export team
  • Hong Kong2010.06
  • India2010.07
  • Philippines2010.07
  • China2010.08
  • Germany2010.09
  • United States2010.12
  • Singapore2011.11
  • Turkey2013.01
  • Russia2013.02
  • Japan2017.11
  • Thailand2019.02
  • Europe2023.05

Request a Quote

A concept is enough to start

Inquiries are processed in the order received, and we will get back to you as soon as possible. We can sign an NDA before we begin.

B2B InquiryTel. +82 2 868 1921 · global@janytree.com · WeChat intomedi

Frequently asked questions

MOQ, development time, cost structure and export support — the questions partners ask before starting.

Read the FAQ

Certification

ISO 22716
CGMP Certified

International standards for cosmetic manufacturing and quality management

Facility

Smart Factory

MES-driven automated production system

Proprietary

Bio-Peptone®
Proprietary Patented Ingredient

Officially listed in the ICID International Cosmetic Ingredient Dictionary

Research

In-House
Dermatological Science Research Institute

Established in 2009 · Holder of 8 patents

Janytree

Specialized Derma-Cosmetic Ampoule Manufacturer

[ABOUT JANYTREE]

Professional
Dermo Cosmetics

Through advanced research into cellular and skin mechanisms and global manufacturing capabilities, Janytree supports the growth of brands in both domestic and international markets.

[CORE TECHNOLOGY]

Technology for
Dermo-Cell Innovation

Janytree’s proprietary technologies deliver high-performance derma-cosmetics by validating both efficacy and safety through skin and cellular science.

[BRAND]

Brand Portfolio

Janytree’s brand portfolio, where expertise meets emotional value.

[SUSTAINABILITY]

Clean. Safe. Responsible

A sustainable manufacturing philosophy for responsible beauty.

Core Technology

Technology for
Dermo-Cell Innovation

Proprietary technologies powered by skin and cellular science, delivering high-performance derma-cosmetics with proven efficacy and safety.

Technology 01

Bio-Peptone®
Fermented Bio-Ingredient Technology

A highly active low-molecular-weight peptide complex created by fermenting pea protein with lactic acid bacteria. A proprietary patented ingredient officially listed in the ICID International Cosmetic Ingredient Dictionary.

  • Enhanced efficacy of active ingredients and improved skin absorption
  • Reduced allergy and irritation factors through fermentation
  • Strengthened skin barrier and anti-inflammatory benefits
  • ICID-listed ingredient with global market competitiveness

Technology 02

TDDS + Device Synergy
Transdermal Drug Delivery System

A transdermal delivery technology that maximizes delivery efficiency by combining micro-channel formation in the skin with high-performance formulations.

  • Increased penetration of active ingredients
  • Skin barrier-friendly delivery mechanism
  • Enhanced skin regeneration and scalp activation effects

Technology 03

High-Concentration Ampoule Stabilization
High-Concentration Formula

Advanced formulation technology that delivers stability, sensory performance, and functionality simultaneously, providing specialized solutions for different skin types and concerns.

  • Design of key ingredients that directly support cellular activity
  • Long-term safety design based on formulation stability assessments
  • Foundation for innovative OEM/ODM product development

Technology 04

Low-Irritation, High-Efficacy Formula
Sensitive-Skin Protocol

Safe, high-performance formulations developed with sensitive skin in mind, supported by high-purity natural ingredient research and skin irritation testing.

  • Research based on high-purity natural ingredients
  • Safety and skin irritation evaluation testing
  • High functionality with minimal irritation

Technology 05

Skin Barrier Formulation Technology
Barrier Science

Advanced delivery technologies utilizing liposomes, biomimetic lipid structures, and nano-delivery systems to optimize absorption and strengthen the skin barrier.

  • Liposome and biomimetic lipid structure technologies
  • Nano-formulation-based delivery systems
  • Intercellular space-friendly design

Category

Multi-Category Development
Full-Spectrum Manufacturing

Comprehensive OEM/ODM development capabilities across a wide range of categories, including skincare, scalp and hair care, body care, and professional skin treatment solutions.

  • Skincare & high-performance ampoules
  • Scalp & hair care solutions
  • Body care

OEM / ODM Partnership

Looking for a premium product development partner?

Janytree promises precise research, refined manufacturing, and responsible quality to help brands secure stronger competitiveness.
From concept planning to R&D, manufacturing, and quality control, we provide comprehensive solutions tailored for premium brands.

With precise formulation design,
we help build premium skincare lines that stand apart.

High-performance formulas backed by skin science